Friday, March 29, 2013

Syria's Assad appeals to African summit for help

DAMASCUS, Syria (AP) ? Syria's increasingly isolated president sent a letter calling for help from leaders of five nations at an economic meeting Wednesday in South Africa to help end his country's civil war.

Bashar Assad's appeal to Brazil, Russia, India, China and South Africa came a day after the Arab League endorsed Syria's Western-backed opposition coalition, allowing it to take the country's seat at a summit in Doha, Qatar. The move drew strong condemnation from Damascus, which warned it will take "appropriate measures" to defend its sovereignty.

Attempts to end Syria's 2-year-old conflict through peaceful means have failed to make progress. The opposition, including the main Syrian National Coalition, says it will accept nothing less than Assad's departure from power while Assad's government has vowed to continue the battle until the rebel forces ? which it refers to as terrorists ? are crushed.

"This requires a clear international will to dry up the sources of terrorism and stop its funding and arming," Assad said in the letter, which was carried by Syrian state media on Wednesday. It was addressed to the leaders at the BRICS forum, which was started in 2009 amid the economic meltdown to chart a new and more equitable world economic order.

Assad said Syria is subjected to "acts of terrorism backed by Arab, regional and Western nations" and asked the leaders to "work for an immediate cessation of violence that would guarantee the success of the political solution."

The opposition's ascension to the Arab League further demonstrated the extent of the regime's isolation two years into a civil war that the U.N. says has killed an estimated 70,000 people.

In a further show of solidarity with anti-Assad forces, the summit in Qatar endorsed the "right of each state" to provide the Syrian people and the rebel Free Syrian Army with "all necessary means to ... defend themselves, including military means."

Following up on the endorsement, the Syrian National Coalition opened what it called its first embassy, raising its green, white and black rebel flag at different site from the now-closed Syrian Embassy in the Qatari capital.

Key opposition figures looked on, including Ghassan Hitto, George Sabra and leader Mouaz al-Khatib, who recently said he was stepping down from his post and criticized the international community for not doing enough to back the anti-Assad forces. Al-Khatib said the SNC will not discuss his resignation, leaving open the option that he could be asked to reverse his decision.

Envoys from the U.S., Turkey, France and other nations that have backed the rebels also attended the ceremony. The new embassy operations are mostly symbolic, but can serve as a base for political initiatives. Many nations in the West, Arab world and elsewhere have declared the SNC the legitimate representative of the Syrian people and have effectively broken diplomatic ties with Assad's government.

Al-Khatib criticized a decision by NATO not to use U.S. Patriot anti-missile batteries based in Turkey to help protect parts of northern Syria from attacks by Assad's military.

But the opposition alliance is marred by severe divisions among its ranks, and often disconnected from the rebel forces fighting inside Syria, so it's not immediately clear how the developments in Qatar would translate on the ground.

The Syrian government said the Arab League's decisions in favor of the opposition "violate in a flagrant way its charter." A statement carried by state-run TV said the Doha summit "encouraged violence, radicalism and extremism that form a danger not only to Syria but for the whole Arab nation and the world."

It said Damascus rejected the Arab summit's decisions and reserved its right "to take appropriate measures to defend its sovereignty and interests of its people." The statement added that Syria will continue the work to "guarantee security and stability and to protect the nation by fighting terrorism and terrorists."

BRICS countries, including Assad's key ally Russia, oppose foreign intervention in Syria and accuse the West of trying to force regime change. Russia, China and South Africa have also voted against U.N. Security Council resolutions on Syria.

At the gathering in the South African coastal resort of Durban, President Jacob Zuma and his Russian counterpart, Vladimir Putin, were asked Tuesday whether they would use their influence to persuade Assad to allow unimpeded U.N. humanitarian access across all of Syria's borders, as requested by leading activists from BRICS countries.

Zuma did not answer, while Putin said only that "We will think about it." Earlier, the Russian president said the forum's leaders would jointly "work for a peaceful resolution to the Syrian crisis."

In his letter, Assad criticized European and U.S. sanctions imposed on his regime and urged leaders of the five countries to "exert every possible effort to lift the suffering of the Syrian people that were caused by the sanctions," an apparent reference to shortages of goods and soaring prices.

Syrian activist groups, meanwhile, reported violence in different areas in the country on Wednesday, including Damascus and its suburbs and the southern Quneitra region along the cease-fire line separating Syria from Israeli-occupied Golan Heights.

The Britain-based Syrian Observatory for Human Rights and the Local Coordination Committees reported clashes and shelling in the Quneitra villages of Bir Ajam, Rasm al-Hawa and Ein el-Darb. The Observatory said rebels overran three army posts near Bir Ajam on Wednesday.

The area near the Golan Heights, a strategic goal of the rebels, has been the scene of heavy clashes for days.

In Israel, the military said it has provided medical care to seven wounded Syrians who arrived at the border of the Israeli-controlled Golan Heights ? the third time Israel has assisted Syrians hurt in the fighting. The two countries are bitter enemies.

The Israeli army said medics treated five Syrians at the border before releasing them back to Syria. It said two other Syrians who were severely wounded were transferred to Israeli hospitals for further treatment.

The army said it will return the wounded Syrians when their hospital treatment ends. Israel did not reveal the identities of the wounded because having been in Israel could endanger them when back in Syria.

___

Mroue reported from Beirut. Associated Press writers Brian Murphy in Doha, Qatar and Josef Federman in Jerusalem contributed to this report.

Source: http://news.yahoo.com/syrias-assad-appeals-african-summit-help-115857816.html

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Thursday, March 28, 2013

Syrian officials: 15 killed in university attack

DAMASCUS, Syria (AP) ? Mortar shells slammed into a cafeteria at Damascus University on Thursday, killing at least 15 people and wounding 20 in what was the deadliest in a string of such attacks on President Bashar Assad's seat of power, state media and officials said.

Rebels began firing shells at the capital earlier this year, and the strikes have become increasingly common in recent weeks as rebels clash with government troops on the east and south sides of the city.

State-run TV said 15 people were killed when mortar shells struck the cafeteria of the university's architecture department in the central Baramkeh district. A Syrian official who spoke to The Associated Press on condition of anonymity because he was not authorized to give official statements said 20 people were wounded in the attack.

There was no immediate claim of responsibility for the attack, which came two days after rebels barraged Damascus with mortar shells that killed at least three people and wounded dozens.

The shelling rarely causes many casualties, but it has shattered the aura of normalcy the regime has tried to cultivate in Damascus. In recent days, rebels have struck deeper than ever into the heart of the city in a new tactic to try and loosen Assad's grip on his main stronghold.

The government blamed "terrorists," the term it uses for rebels fighting to oust Assad, and called the attack as a "barbaric massacre."

Government-run Al-Ikhbariya TV showed footage of plastic tables and chairs turned upside down, shattered glass and pens and books scattered on the floor. Pools of blood were seen on the floor of the open-air cafeteria. The station showed paramedics trying to revive a wounded girl.

The Britain-based Syrian Observatory for Human Rights confirmed the attack, saying many of the wounded were in critical condition.

Syria's crisis began in March 2011 with protests demanding Assad's ouster. Following a harsh government crackdown, the uprising steadily grew more violent until it became a full-fledged civil war. The U.N. says Syria's two-year civil war has killed more than 70,000 people.

The mortar attack at the university occurred as officials denied opposition claims that an Iranian cargo plane allegedly carrying weapons to Assad's regime was hit as it landed at Damascus International Airport.

Al-Arabiya and Al-Jazeera TV quoted activists as saying that the plane was hit Wednesday night and caught fire as it was landing. State-run TV denied the report while the Observatory chief, Rami Abdul-Rahman, said he could not confirm that such an incident happened.

Ghaidaa Abdul-Latif, the general director of the Syrian Arab Airlines, denied in a telephone interview with The AP the occurrence of any incident at the airport. She stressed that all reports about the incident were "absolutely untrue."

Earlier in the day, activists said Syrian rebels attacked army checkpoints in and around a key southern town that is a gateway to Damascus.

The Observatory said rebel attacks were under way in and around Dael in the strategic Daraa province, which borders Jordan. The Local Coordination Committees, another activists group, said regime bombardment of Dael killed at least three people on Thursday.

The Observatory also reported violence in other parts of Syria, including the northern regions of Idlib and Aleppo, and air raids on the suburbs of Damascus.

The fighting comes as Mideast powers opposed to Assad have stepped up weapons supplies to Syrian rebels in coordination with the U.S. in preparation for a push on the Syrian capital, according to officials and military experts who spoke to the AP in Jordan.

In Jordan, the U.N. refugee agency said a riot broke out at a refugee camp for Syrians in the country after some of the refugees were told they could not return home.

Ali Bibi, a U.N. refugee liaison officer in Jordan, said it was unclear how many refugees were involved in Thursday's melee at the Zaatari camp. The riot broke out after some Syrians in the camp tried to board buses to return to their country.

He said Jordanian authorities refused to let the buses head to the border because of ongoing clashes between the rebels and Assad's forces in southern Syria, just across the border from Jordan. Bibi said there were no immediate reports of injuries.

Turkish officials on Thursday denied reports that the country was deporting several hundreds of Syrian refugees for causing disturbances inside a refugee camp near the border. A Foreign Ministry official said, however, that a group of 100 refugees asked to be allowed to leave the camp and to return to Syria on their own free will.

A fire at the camp in the town of Akcakale late Wednesday killed a 7-year-old child and sparked unrest among the refugees.

A camp security official said local authorities identified about 300 people who allegedly caused the disturbance and prepared to deport them. But the move was stopped by government officials, he said. He spoke on condition of anonymity because he was not allowed to discuss the situation in the camp with journalists.

The U.N. refugee agency could not immediately confirm the reports, but said it was concerned by allegations of possible deportations from Akcakale and was seeking further information.

In Israel, the military said it was beefing up medical teams along the border with Syria following several cases of wounded Syrians crossing the frontier to seek medical assistance.

A military official, who spoke on condition of anonymity under military protocol, said on Thursday there have been "numerous incidents" in recent months in which Syrians wounded in the fighting in their country arrived at the frontier for first aid from Israeli medics.

Eleven of them were taken and treated at Israeli hospitals, including one who died from his wounds on Wednesday. Others returned home after their conditions have improved.

The official spoke on condition of anonymity under military protocol. He said the military's focus in the Israeli-held Golan Heights was still on security and defense but that Israel sent extra medical teams to the area realizing more wounded could soon arrive.

___

Associated Press writers Bassem Mroue in Beirut, Suzan Fraser in Ankara Turkey, Josef Federman in Jerusalem and Dale Gavlak in Amman, Jordan, contributed to this report.

Source: http://news.yahoo.com/syrian-officials-15-killed-university-attack-140256813.html

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Asia stocks weighed down by Europe debt woes

(AP) ? Renewed jitters about the debt crisis in Europe sent Asian stock markets lower Thursday.

Banks in Cyprus are due to open later Thursday for limited banking only after being shut for nearly two weeks as an emergency loan was being pieced together to prevent the nation's financial sector from collapsing.

The agreement reached late Monday with international lenders gives Cyprus a 10 billion euro ($12.9 billion) bailout but forces losses on depositors with more than 100,000 euros in the country's two largest banks.

Evan Lucas of IG Markets in Melbourne said the deal has sparked fears it may be repeated in other European nations that faced similar circumstances. In an email commentary, he said investors saw the deal "as a monster in the shadows for banks in Portugal, Spain and Italy" since it requires depositors ? not the public or its tax contributions ? to take the pain.

Japan's Nikkei 225 index tumbled 1.6 percent to 12,300.42. Hong Kong's Hang Seng lost 1.1 percent to 22,214.61. South Korea's Kospi slipped 0.2 percent at 1,990.04. Australia's S&P/ASX 200 lost 0.2 percent to 4,984.30.

Investors are waiting to see the reaction later Thursday, when Cypriot banks open their doors. Authorities have been putting measures in place to prevent a rush of euros out of the country's banks. Cash withdrawals will be limited to 300 euros ($383) per person each day, and no checks will be cashed.

Peter Lai of DBS Vickers Securities in Hong Kong said he was expecting a "disastrous phenomenon" in Cyprus when banks reopen.

"We also expect there'll be some kind of bank run. So lots of people are trying to get their cash back and this undoubtedly will be some kind of bad impact on the Cyprus banking system and people believe that or they think that this may affect the euro system," he said.

Meanwhile, in Italy, a leading political party failed in its attempt to form a new government. The stalemate has raised concerns that the country will be unable to manage its deep debts. Italy is the third-largest economy of the 17 countries that use the euro.

Financial stocks across Asia slumped. Japan's Mizuho Financial Group dropped 2.4 percent. Agricultural Bank of China fell 2.9 percent in Hong Kong.

In Australia, Newcrest Mining plummeted 7.9 percent after the company said its gold production target for the 2012-13 fiscal year would not be reached.

Wall Street stocks closed mostly lower Wednesday on Europe worries. The Dow Jones industrial average dropped 0.2 percent to close at 14,526.16. The S&P 500 fell less than 0.1 percent to close at 1,562.85. The Nasdaq composite index rose 0.1 percent to 3,256.52.

Benchmark oil for May delivery was up 7 cents to $96.65 per barrel in electronic trading on the New York Mercantile Exchange. The contract gained 24 cents to close at a five-week high of $96.68 per barrel on the Nymex on Wednesday.

In currencies, the euro rose to $1.2783 from $1.2774 late Wednesday in New York. The dollar fell to 94.06 yen from 94.38 yen.

___

Follow Pamela Sampson on Twitter at http://twitter.com/pamelasampson

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-03-28-World%20Markets/id-68b9ac315fb74bf58e768bd11229c40f

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Orbino Padova Mini for iPad mini review

Orbino has recently released its new Padova Mini Case for the iPad mini. Like its larger sibling,?the miniPadova is a form-fitting flip-style case that is hand-stitched with thick waxed thread and constructed from fine Italian leather or rare animal skins. I have reviewed other?Orbino accessories?in the past and have yet to be disappointed in their [...]

Source: http://the-gadgeteer.com/2013/03/27/orbino-padova-mini-for-ipad-mini-review/

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Uncovering Africa's oldest known penguins

Mar. 26, 2013 ? Africa isn't the kind of place you might expect to find penguins. But one species lives along Africa's southern coast today, and newly found fossils confirm that as many as four penguin species coexisted on the continent in the past. Exactly why African penguin diversity plummeted to the one species that lives there today is still a mystery, but changing sea levels may be to blame, the researchers say.

The fossil findings, described in the March 26 issue of the Zoological Journal of the Linnean Society, represent the oldest evidence of these iconic tuxedo-clad seabirds in Africa, predating previously described fossils by 5 to 7 million years.

Co-authors Daniel Thomas of the National Museum of Natural History and Dan Ksepka of the National Evolutionary Synthesis Center happened upon the 10-12 million year old specimens in late 2010, while sifting through rock and sediment excavated from an industrial steel plant near Cape Town, South Africa.

Jumbled together with shark teeth and other fossils were 17 bone fragments that the researchers recognized as pieces of backbones, breastbones, wings and legs from several extinct species of penguins.

Based on their bones, these species spanned nearly the full size spectrum for penguins living today, ranging from a runty pint-sized penguin that stood just about a foot tall (0.3 m), to a towering species closer to three feet (0.9 m).

Only one penguin species lives in Africa today -- the black-footed penguin, or Spheniscus demersus, also known as the jackass penguin for its loud donkey-like braying call. Exactly when penguin diversity in Africa started to plummet, and why, is still unclear.

Gaps in the fossil record make it difficult to determine whether the extinctions were sudden or gradual. "[Because we have fossils from only two time periods,] it's like seeing two frames of a movie," said co-author Daniel Ksepka. "We have a frame at five million years ago, and a frame at 10-12 million years ago, but there's missing footage in between."

Humans probably aren't to blame, the researchers say, because by the time early modern humans arrived in South Africa, all but one of the continent's penguins had already died out.

A more likely possibility is that rising and falling sea levels did them in by wiping out safe nesting sites.

Although penguins spend most of their lives swimming in the ocean, they rely on offshore islands near the coast to build their nests and raise their young. Land surface reconstructions suggest that five million years ago -- when at least four penguin species still called Africa home -- sea level on the South African coast was as much as 90 meters higher than it is today, swamping low-lying areas and turning the region into a network of islands. More islands meant more beaches where penguins could breed while staying safe from mainland predators.

But sea levels in the region are lower today. Once-isolated islands have been reconnected to the continent by newly exposed land bridges, which may have wiped out beach nesting sites and provided access to predators.

Although humans didn't do previous penguins in Africa in, we'll play a key role in shaping the fate of the one species that remains, the researchers add.

Numbers of black-footed penguins have declined by 80% in the last 50 years, and in 2010 the species was classified as endangered. The drop is largely due to oil spills and overfishing of sardines and anchovies -- the black-footed penguin's favorite food.

"There's only one species left today, and it's up to us to keep it safe," Thomas said.

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Story Source:

The above story is reprinted from materials provided by National Evolutionary Synthesis Center (NESCent), via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Daniel B. Thomas, Daniel T. Ksepka. A history of shifting fortunes for African penguins. Zoological Journal of the Linnean Society, 2013; DOI: 10.1111/zoj.12024

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/sBXiGc1qknY/130326101606.htm

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Wednesday, March 27, 2013

Japan grants a loan to Morocco's National Bureau of Water and ...

By Youssef Sourgo

Morocco World News

Casablanca, March 27, 2013

The Japanese Agency for International Cooperation granted the National Bureau of Water and Electricity a loan of 10.79 million yen ($ 114 million) to support a liquid cleansing program, according to the daily newspaper Al Akhbar Almaghrbya.

The agreement was signed on Tuesday in Japan by the Director General of the National Office of Water and Electricity, Mr. Ali Fassi Fihri, and the President of the Japanese Agency for international Cooperation, Mr. Akihiko Tanaka, in the presence of the Ambassador of Morocco in Japan, Mr. Samir Oarour.

The National Office for Water and Electricity affirmed that the interest rate does not exceed 0.3 % over a period of 40 years, 10 years of which are exempted.

The Japanese Agency for International Cooperation aims to support the cleansing project that the Bureau seeks to accomplish through the renovation and expansion of filtering capabilities, as well as solidifying the capacity of assembling wastewater for a population of around 1 million people, which will eventually contribute to improving the living conditions of the population.

Source: http://www.moroccoworldnews.com/2013/03/84198/japan-grants-a-loan-to-moroccos-national-bureau-of-water-and-electricity/

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Tuesday, March 26, 2013

Amazon still featuring porn as 'teen books for girls'

amazon

3 hours ago

NBC Chicago video of grandmother on laptop

NBC Chicago

It has been nearly four months since Martha Welter first alerted Amazon.com that a search for "teen books for girls" yielded scores of pornographic books on its website. Not only are the books still there, but dozens more have been added, many of them more graphic than before.

What?s more, it appears that the books' publishers may be intentionally targeting these books to teen girls.

For source documents and video coverage, check out the original piece at NBCChicago.com.

As NBC5 Investigates first reported last December, Welter ? a Chicago grandmother ? logged on to Amazon the Monday after Thanksgiving to look for a Christmas present for her 12-year-old granddaughter.

"I always give books to my grandkids for Christmas," she said at the time.

Welter, a frequent Amazon shopper, began her search by typing the word "teen" into Amazon?s search box. A drop-down menu suggested a search for "Teen Books for Girls," so she clicked on it, and then looked for the newest books available.

"I go through the first page, and that?s fine," she said. "And I go to the second page, and there I find adult picture books ? adult, pornographic picture books."

And not just a few: NBC5 Investigates replicated Welter?s search at the time, and found that 91 out of a total of 140 books featured as Amazon?s newest "teen books for girls," were, in fact, adult picture books, most with graphic covers that were impossible to avoid while paging through the search results.

Welter immediately alerted Amazon.

"I [couldn?t] imagine that they would be doing this intentionally," she said.

It took a few days, but she finally got a rather baffling email response from an Amazon customer service representative.

NBC Chicago screenshot of Amazon bikini girl

NBC Chicago

"Hello," it said: "From your message I understand that you have seen some Pornographic books in recent releases of books for teen girls. I appreciate you taking the time to share your opinions about website information. We introduced this feature so that individuals using our web search feature would be presented with the opportunity to discover related items of interest."

"Who do they think is 'interested'?" Welter said. "Me or my teen granddaughter?"

The customer service email continued: "I?ve passed your message on to the appropriate people in our company. ... Thank you for your inquiry. Did I solve your problem?"

Since the answer was no, Welter continued to send emails and write letters in an effort to get Amazon.com to take down the books, with no results. NBC5 also sent several emails and left even more voice mails for Amazon.

he company never responded, and the "books" remained online into the new year.

Now, they?ve multiplied.

Seventeen weeks after Welter first alerted Amazon, a search for recently-published Kindle versions of "Teen Books for Girls" yields prominent photos of topless or near-naked women and titles like "Sexy Asian Girl?s Desire (Adult Picture Book)," "Rip Off My Stockings," and even "Daddy Daughter Taboo Sex Stories (Family Sex)," amidst such innocent titles as "Emily of New Moon," "Blinky Bill and Nutsy," and even "Keeping Your Kids Safe."

In observance of NBC?s own standards and practices, most of the book titles can?t be listed here.

NBC5 Investigates' most recent count shows that more than half of the most-recently-published Kindle books listed as "Teen Books for Girls," ? 104 books out of the most recent 200 ? are adult books. What?s more, each book?s URL, the unique web address generated when the book is published online, actually includes the term "teen-books-for-girls," suggesting it is no accident that the books are appearing in this search geared towards teenagers.

Without a response from Amazon, it is difficult to know just how these books have made their way into a search which anyone, including any child, can do. But it appears the books are being uploaded through Amazon?s Kindle Direct Publishing service, which Amazon advertises online as "the fast and easy way to self-publish your books for sale in the Kindle Store." The site allows any self-publisher to define how and where his or her "book" will be classified in Amazon, and allows the publisher to create the key words that will target the book online.

The service?s "Content Guidelines" state: "We don?t accept pornography or offensive depictions of graphic sexual acts. ? What we deem offensive is probably about what you would expect."

That appears to be Amazon?s guidelines for all such Kindle books, including those found in an innocent search for a book for a 12-year-old girl.

More from NBC Chicago:

Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2a039f7d/l/0L0Stoday0N0Ctech0Camazon0Estill0Efeaturing0Eporn0Eteen0Ebooks0Egirls0E1C90A79970A/story01.htm

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Cypriot youth protest as banks stay shut

By Michele Kambas and Costas Pitas

NICOSIA (Reuters) - Cypriots vented anger in the streets on Tuesday and were desperate to learn what would happen to their savings, with the government yet to reveal details of controls it will impose to prevent a run when banks reopen after a painful bailout.

A special administrator was appointed to run the country's biggest bank, which will take over accounts from the second biggest bank as part of the restructuring package designed to bail out and rein in the oversized financial sector.

Cyprus's banks were ordered to remain closed until Thursday, and even then will operate under as-yet-undisclosed capital controls imposed to prevent depositors from emptying the vaults.

The Central Bank governor said the controls would be "loose" and would apply to all banks in the country. The restrictions would be "temporary" but he would not say what form they would take or how long they would last. Earlier, the finance minister said they could be in place for weeks.

Cyprus had faced bankruptcy and potential ejection from the European single currency without a rescue deal with international lending bodies. Now that the deal has been struck, it faces job losses and economic contraction.

Reuters journalists estimated up to 3,000 high school students protested outside parliament, the first major expression of popular anger after Cyprus agreed the 10 billion euro ($13 billion) bailout with the European Union.

"They've just gotten rid of all our dreams, everything we've worked for, everything we've achieved up until now, what our parents have achieved," said a student who gave his name as Thomas.

Outside the central bank, about 200 employees of the country's biggest commercial bank, the Bank of Cyprus, demanded the resignation of the central bank governor, Panicos Demetriades, chanting "Hands off Cyprus" and "Disgrace".

"We are scared. We were also so proud of the Bank of Cyprus. We worked with a lot of love, not just for the money," said a Bank of Cyprus worker who gave her name as Anthoulla.

RESIGNATION

Under the bailout, the second largest bank, Cyprus Popular Bank, is to be shut down and its accounts of under 100,000 euros combined with those of the Bank of Cyprus. Accounts of more than 100,000 euros at both banks will be frozen, with depositors, many of them rich foreigners, likely to lose much of their investments.

Dinos Christofides, an accountant and banker, told Reuters he had been named administrator to run the Bank of Cyprus: "It means that from now until further notice I will be running the bank. It could be short term ... or it could be longer."

Bank of Cyprus chairman Andreas Artemis offered to resign on Tuesday, a source at the bank said. His fate was not clear after the bank declined to accept his resignation.

After returning from last-ditch negotiations in Brussels, Cypriot President Nicos Anastasiades said late on Monday that the rescue plan agreed was "painful" but essential.

European leaders said the deal averted a chaotic national bankruptcy that might have forced Cyprus from the euro.

A Cyprus exit from the euro would be "disastrous, politically and economically" and was not to be contemplated, Finance Minister Michael Sarris said.

By protecting state guaranteed deposits of up to 100,000 euros, the bailout reversed a previous deal that would have imposed a levy on small depositors as well as big ones, which had infuriated Cypriots and was vetoed by parliament. Sarris said big depositors could face loses of around 40 percent.

Many Cypriots say they do not feel reassured by the new deal, however, and are expected to besiege banks as soon as they reopen after a shutdown that began over a week ago.

Reversing a previous decision to start reopening at least some banks on Tuesday, the central bank said late on Monday that all banks would now stay shut for two more days to ensure the "smooth functioning of the whole banking system".

TEMPORARY MEASURE

Little is known about the restrictions on transactions that Anastasiades said the central bank would impose, but he told Cypriots: "I want to assure you that this will be a very temporary measure that will gradually be relaxed."

Such controls are at odds with the European Union's ideals of a common market but the government is anxious to prevent any panic that would cause even more disruption to the economy.

The central bank has imposed a 100-euro daily limit on withdrawals from cash machines at the two biggest banks.

Without an agreement by the end of Monday, Cyprus risked becoming the first country to be pushed out of the European single currency - a fate Germany and other northern creditors seemed willing to inflict.

BUSINESS LIFE

The closure of the banks for more than a week has hurt business. Andreas Hadjiadamou, president of the Cyprus Supermarkets Association, said: "It's had a huge effect on the market. Consumers' psychology has hit the floor."

"If they (the banks) don't open on Thursday we could see supply problems as well as delays in salary payments."

Maria Benaki, who runs a family silverware business on Nicosia's biggest shopping street, said she hasn't had a customer in days.

"The situation is dire. I don't understand why we bother coming into work at all to be honest," she said. "What will happen at the end of the month when I need to pay my bills?"

(Additional reporting by Jan Lopatka in Prague, Catherine Bremer in Paris; Writing by Giles Elgood; Editing by Peter Graff)

Source: http://news.yahoo.com/cyprus-banks-remain-closed-avert-run-deposits-062008464.html

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Erdogan: Israel must act on agreement before normalized ties

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Source: http://feedproxy.google.com/~r/jta/breaking-news/~3/NdTkVyUjW8A/erdogan-says-normalization-with-israel-will-take-time-and-action

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Monday, March 25, 2013

Aye-ayes: Endangered lemurs' complete genomes are sequenced and analyzed for conservation efforts

Mar. 25, 2013 ? For the first time, the complete genomes of three separate populations of aye-ayes -- a type of lemur -- have been sequenced and analyzed in an effort to help guide conservation efforts. The results of the genome-sequence analyses will be published in an early edition of Proceedings of the National Academy of Sciences online during the week of March 25.

The team of scientists is led by George H. Perry, assistant professor of anthropology and biology at Penn State University; Webb Miller, professor of biology and of computer science and engineering at Penn State; and Edward Louis, director of conservation genetics at Omaha's Henry Doorly Zoo and Aquarium and director of the Madagascar Biodiversity Partnership, NGO.

The aye-aye -- a lemur that is found only on the island of Madagascar in the Indian Ocean -- recently was re-classified as "endangered" by the International Union for the Conservation of Nature. "The aye-aye is one of the world's most unusual and fascinating animals," said Perry. "Aye-ayes use continuously growing incisors to gnaw through the bark of dead trees and then a long, thin, and flexible middle finger to extract insect larvae, filling the ecological niche of a woodpecker. Aye-ayes are nocturnal, solitary and have very low population densities, making them difficult to study and sample in the wild."

Perry added that he and other scientists are concerned about the long-term viability of aye-ayes as a species, given the loss and fragmentation of natural forest habitats in Madagascar. "Aye-aye population densities are very low, and individual aye-ayes have huge home-range requirements," said Perry. "As forest patches become smaller, there is a particular risk that there won't be sufficient numbers of individual aye-ayes in a given area to maintain a population over multiple generations. We were looking to make use of new genomic-sequencing technologies to characterize patterns of genetic diversity among some of the surviving aye-aye populations, with an eye towards the prioritization of conservation efforts."

Louis, with his team at Omaha's Henry Doorly Zoo and Aquarium and the Madagascar Biodiversity Partnership, worked to locate aye-ayes and collect DNA samples from three separate regions of Madagascar: the northern, eastern, and western regions. To discover the extent of the genetic diversity in present-day aye-ayes, the researchers generated the complete genome sequences of 12 individual aye-ayes. They then analyzed and compared the genomes of the three populations. They found that, while eastern and western aye-ayes are somewhat genetically distinct, aye-ayes in the northern part of the island and those in the east show a much more significant amount of genetic distance, suggesting an extensive period of time during which interbreeding has not occurred between the populations in these regions.

"Our next step was to compare aye-aye genetic diversity to present-day human genetic diversity," explained Miller. "This analysis can help us to gauge how long the aye-aye populations have been geographically separated and unable to interbreed." To make the comparison, the team gathered 12 complete human DNA sequences -- the same number as the individual aye-aye sequences generated -- from publicly available databases for three distinct human populations: African agriculturalists, individuals of European descent, and Southeast Asian individuals. Using Galaxy -- an open-source, web-based computer platform designed at Penn State for data-intensive biomedical and genetic research -- the team developed software to compare the two species' genetic distances. They found that present-day African and European human populations have a smaller amount of genetic distance than that found to exist between northern and eastern aye-aye populations, suggesting that the aye-aye populations were separated for an especially lengthy period of time by geographic barriers.

"We believe that northern aye-ayes have not been able to interbreed with other populations for some time. Although they are separated by a distance of only about 160 miles, high and extensive plateaus and major rivers may have made intermingling relatively infrequent," explained Miller. He added that the results of the team's data further suggest that the separation of the two aye-aye populations stretches back much longer than 2,300 years, which is when human settlers first arrived on the island and started burning the aye-ayes' forest habitat and hunting lemurs.

The team members hope that their findings will help to guide future conservation efforts for the species. "This work highlights an important region of aye-aye biodiversity in northern Madagascar, and this unique biodiversity is not preserved anywhere except in the wild," said Louis. "There is tremendous historical loss of habitat in northern Madagascar that is continuing at an unsustainable rate today. This study is an excellent example of how a comprehensive and coordinated effort in the field and laboratory can identify previously unknown patterns of biodiversity for an endangered species, which then can be used by conservation organizations to base their management strategies."

The authors added that, in future research, they would like to sequence the genomes of other lemur species -- more than 70 percent of which are considered endangered or critically endangered -- as well as aye-ayes from the southern reaches of the island of Madagascar.

In addition to Perry, Miller, and Louis, other scientists who contributed to this research include Stephan C. Schuster, Aakrosh Ratan, Oscar C. Bedoya-Reina, and Richard Burhans from Penn State; Runhua Lei from the Center for Conservation and Research at Omaha's Henry Doorly Zoo and Aquarium; and Steig E. Johnson from the University of Calgary in Alberta, Canada.

Funding for aye-aye sample collection was provided by Conservation International, the Primate Action Fund, and the Margot Marsh Biodiversity Foundation, along with logistical support from the Ahmanson Foundation and the Theodore F. and Claire M. Hubbard Family Foundation. Additional support comes from the National Institutes of Health, the National Science Foundation, the Pennsylvania Department of Health, and the College of the Liberal Arts at Penn State University.

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The above story is reprinted from materials provided by Penn State. The original article was written by Katrina Voss.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. George H. Perry, Edward E. Louis, Jr., Aakrosh Ratan, Oscar C. Bedoya-Reina, Richard C. Burhans, Runhua Lei, Steig E. Johnson, Stephan C. Schuster, and Webb Miller. Aye-aye population genomic analyses highlight an important center of endemism in northern Madagascar. PNAS, March 25, 2013 DOI: 10.1073/pnas.1211990110

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/th-V7_WkuQM/130325160507.htm

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Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms

Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms

Monday, March 25, 2013

Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists from the University of Western Ontario have discovered certain strains of lactobacillus bacteria are capable of dampening production of that toxin according to research published in the journal Applied and Environmental Microbiology.

"The risk of potentially fatal toxic shock syndrome appears to be influenced by the types of bacteria present in the vagina," says principal investigator Gregor Reid.

In planning the study, "I figured that the Staphylococcus aureus strains with the ability to produce toxic shock syndrome toxin might only do this under certain environmental conditions," says Reid. "In the vagina, that means depending on pH and the other bacteria living there."

The researchers took swabs from women with clinically healthy vaginal status, with intermediate status, and from those diagnosed with bacterial vaginosis. They then identified the bacterial species, and assayed for toxic shock syndrome toxin 1. "In particular, Streptococcus agalactiae, often referred to as Group B streptococci, an organism of particular concern when giving birth, increased toxin production 3.7-fold," says Reid. But various species of lactobacillus repressed toxin production, one by 72 percent.

"These experiments emphasize that for proper clinical care of women, we need to know all bacterial types present in the vagina," says Reid. "Culturing is inadequate, and while some microscopy is feasible if the viewer develops the expertise to assess the vaginal smears, rapid 16s sequencing systems are needed as a diagnostic tool," because many species are "very difficult to culture," or have never been cultured.

"We need to vastly improve how we diagnose infections and determine the risk of infection of women," says Reid. He also recommends "improving our ability to manipulate microbiota [with probiotics] in lieu of using broad spectrum antibiotics that were developed 40 years ago, and are not very effective in the vagina, and certainly not designed to neutralize toxins."

###

American Society for Microbiology: http://www.asm.org

Thanks to American Society for Microbiology for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127414/Certain_bacteria_suppress_production_of_toxic_shock_toxin__Probiotic_potential_looms

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Sunday, March 24, 2013

2013 NFL Free Agency: Final grade for the Titans

The Titans might still have a move or two left in them, but they are done with the major moves at this point. I love that they went after it this free agency period. They were able to address most of their needs, and it will really free them up to draft whoever they want in next month's draft.

This camp is also going to be the first one in a while where there has been legitimate competition for starting spots. They have had "camp battles" the last couple of years, but they have always been more about a back-up spot or the last roster spot.

I would have really liked to see them add one of the veteran pass rushers, but it doesn't appear that is going to happen at this point.

They still get a B+ from me. They would have gotten an A if they added that pass rusher, but still a solid effort.

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Source: http://www.musiccitymiracles.com/2013/3/24/4141268/2013-nfl-free-agency-grades-titans

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Some Pebble smartwatches bricking after shutdown, company replacing faulty units

It appears that Pebble's smartwatch is officially feeling its largest growing pain since debuting just two months ago. A five-page long (and growing) thread on the company's forum has some owners describing a bug that's leaving their Pebbles pebbled bricked after shutdown. Pebble's Eric Migicovsky let us know that the company is actively replacing affected units, while examining those being sent in to find out the root cause:

We've had reports of this issue, and we understand of course that it's annoying for users. We're replacing any Pebbles for users who report this issue. We're reviewing the Pebbles that get returned, working to get to the bottom of the issue. We have our support team ready to follow up to any user that reports this issue.

As it stands, there's no word on whether firmware update 1.9 has any role in keeping the devices from turning on after being shut down. Owners have further reported that no amount of charging their Pebble will help it to actually come back to life. We've reached out to the company for more info on the matter (including nailing down how many units the company has replaced so far), and we'll be sure to keep you updated. For now, let us know whether your experience with Pebble has been rocky at all so far.

Update: That was fast -- apparently Pebble has received about 30 reports of this issue since Friday. Here's the official word from Migicovsky:

We're tracking a few reports of this issue. Up to Friday, we've had 20-30 reports (out of 30,000+ pebbles in the field). We've gotten several back to the office, and we're getting to the bottom of it.

[Thanks to everyone who sent this in]

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Comments

Source: Pebble (forum)

Source: http://www.engadget.com/2013/03/23/pebble-smartwatch-dead-after-shutdown-report-owners/

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Jonathan Smith: Hope at the Epicenter: Overcoming the TB Emergency in Sub-Saharan Africa

I met her while conducting research in 2011. She had never had tuberculosis (TB). She was HIV negative. But sitting on her bed beside her husband in the Eastern Cape of South Africa, she quietly asked,

"Do we have hope?"

I paused -- partly because I was stunned, partly because for a moment I had no idea how to answer. In my brief reverie, I could hear the wheezing of her husband's advanced silicosis -- a debilitating fibrotic disease of the lung caused by years of working in the underground mines. I could see the absolute emaciation caused from the TB in his lungs.

If she had of asked me if he had hope, my reply may have been unfortunate, perhaps a bit crass, but simple.

But that's not what she asked. She asked if we had hope. So after a moment of hesitation, I responded with the most complicated phrase I could imagine.

"Of course, madame."

For well over a century, South Africa miners, their families, and communities have been decimated by tuberculosis. The South African mines have the highest recorded rates of TB in the world and an entrenched system of migrant labor bridges these areas of high concentration with the rural home areas. This link between mining and TB among the general public is palpable: mining contributes to an estimated 760,000 cases of TB in the southern African region.

Just two years ago, my response to the miner's wife was born out of pure optimism and a commitment to bring this human tragedy to an end. But, the current momentum in the region suggests that we may have had good reason to be hopeful.

In August 2012, the Heads of State of 15 Southern African Development Community (SADC) member states signed a Declaration on TB in the Mining Sector, which could be regarded as one of the largest acts of political will the TB community has ever seen. Unlike typical political rhetoric, this declaration specifically calls on civil society, international governments, and the corporate sector as partners at the table.

It recognizes the need for cooperative leadership among these groups, and embraces accountability. It avoids the intellectually lazy trap of demonizing the mining industry, recognizing that though they are part of the problem, they are also part of the solution. It calls of partners from around the globe to come together and be more than the sum of their individual parts for a collective impact response.

The declaration is not enough on its own.

First, it must be backed up with targeted investments. That means a fully funded Global Fund. The Fund provides the vast majority of international financing for TB programs and without it the fight against TB will grind to a halt. But we also need new streams of financing. As the WHO and Global Fund stated earlier this week, there is an annual gap in international financing for TB of at least $1.6 billion a year.

Second, the Declaration must lead to real partnerships. It was heartening to see industry come together with the mining industry and government in Swaziland yesterday and commit to accelerating action on TB and HIV in the next 1,000 days. This was backed up with funding from organizations including the Global Fund and the Stop TB Partnership which is now helping to track down and treat former miners whose TB might otherwise have gone undetected.

It is even more encouraging the South Africa government, in partnership with the World Bank and others, will hold a summit on TB and Mining later in the year. The SADC governments are showing sustained dedication on this issue, and are clearly working to ensure that the Declaration does not lose its momentum like so many political acts of will throughout history.

Does this mean that the saying of migrant miners in Southern Africa "returning home to die" is no longer accurate? Sadly, not yet. But the two years since I responded to her with my cautious optimism have been accompanied by unprecedented progress on the issue. So I'll stick by my first response to the miner's wife. Yes, we do have hope.

This post is part of a series produced by The Huffington Post, The Global Fund, and the Stop TB Partnership in recognition of World TB Day. For more information on The Global Fund, click here. To read more posts about The Big Push -- The Global Fund's effort to eradicate HIV/AIDS, malaria and tuberculosis -- click here.

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Source: http://www.huffingtonpost.com/jonathan-smith/tb-in-sub-saharan-africa_b_2936394.html

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Saturday, March 23, 2013

7 tax return pitfalls to avoid - Business Management Daily

Besides the usual problems bedeviling late filers, several recent tax law changes may cause complications on your 2012 return. Follow these seven steps to avoid problems. ?

1.??Enter at your own risk. Many of the usual math errors are eliminated if you use tax preparation software that does the grunt work for you. But that doesn?t mean you?re home-free. You still have to enter the information accurately, either on paper or electronically, on Form 1040. For instance, if your W-2 reflects a salary of $175,000 and you mistakenly enter $157,000 on your tax return, you will substantially underpay your 2012 tax liability.

Double-check your entries and any math you?re doing on your own. Year in and year out, these errors remain the biggest bugaboo for tax filers.

Tip: IRS computers match up income reported on W-2s and 1099s to returns. If the agency finds discrepancies, you could be assessed extra tax plus interest and penalties.? ...(register to read more)

To read the rest of this article you must first register with your email address.

Source: http://www.businessmanagementdaily.com/35038/7-tax-return-pitfalls-to-avoid-and-5-tax-breaks-not-to-miss

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Couples leading Prop. 8 fight: 'We are very excited to have the end in sight'

Justin Sullivan/Getty Images

SAN FRANCISCO, CA - DECEMBER 06: (L-R) Same sex couples and plaintiffs Sandy Stier, Kris Perry, Paul Katami and Jeffrey Zarrillo look on at a news conference following a hearing at the Ninth Circuit Court of Appeals on December 6, 2010 in San Francisco, California.

By Miranda Leitsinger, Staff Writer, NBC News

Two gay California couples who are leading the legal fight to overturn the state's ban on same-sex marriage said Thursday on the eve of their landmark Supreme Court hearing that they were relieved to have "the end in sight" and believe the justices will step in "to right these wrongs."

Kris Perry and Sandy Stier, and Paul Katami and Jeff Zarrillo, are the faces to the challenge to Proposition 8, a citizen's initiative denying gays and lesbians the right to wed that voters approved in a pitched multi-million dollar ballot battle in 2008. The court will hear arguments in the case on Tuesday.

?The right thing for the justices to do is to lead the country on including all of us in this institution and finding a way to equity and fairness that brings the country together rather than dividing us based on a characteristic that we cannot change,? Perry said on a call to reporters.?

Photo by Kevork Djansezian/Getty Images

Plaintiffs Kris Perry (L) kisses her partner Sandy Stier during a rally to celebrate the ruling to overturn Proposition 8 on August 4, 2010 in West Hollywood, California.

?There is an opportunity here for the court to send a message that who we love is important and we should be treated equally under the law," she added.

The couples will be in Washington, DC, for the historic hearing, which comes one day before the justices hear arguments contesting the constitutionality of a federal law, the Defense of Marriage Act (DOMA), that bars recognition of same-sex marriage and thereby denies more than 1,100 benefits to gay and lesbian couples.?

"We both are very relieved and excited by the prospect of the final chapter in this case happening in the next few months,? Perry said, adding that they have "been waiting a very long time to be married and to celebrate that with our children and our parents. ? I know that we are both very excited to have the end in sight."

The couples' journey began years earlier, when they decided to join the legal effort and testified before lower courts about the impact the ban has had on their lives. They further entered the public realm as advocates, doing interviews and television/online spots about their campaign.

Photo by Kevork Djansezian/Getty Images

Lawyer Theodore Olson (L) and his clients Paul Katami (C) and his partner Jeff Zarrillo attend a rally to celebrate the ruling to overturn Proposition 8 on August 4, 2010 in West Hollywood, California. A federal judge overturned California's Proposition 8, a same-sex marriage ban, finding it unconstitutional.

?All four of us have regular lives and we have jobs that we need to pay our bills and so we have to be able to plug in and unplug when that happens,? said Zarillo, of Burbank. ?But being a part of this case, and being so closely associated with it, it reminds us of the daily harm and that discrimination even more every day.?

The legal struggle, he added, also ?made us closer as a couple and has made us want access to that language even more, because the word 'marriage' and the word 'husband' and the word 'wife,' they have meaning? to society, family and children.?

?It affirms the commitment that we have built and shared,? he said. ?While some people say it's just a word, that word is so important. And if it wasn't so important, we wouldn't even be having this conversation."

Stier, of Alameda, said being a part of the case has impacted their lives in a ?dramatic way.? Two of the couple's four boys were headed to college when they joined the fight, but another two were just starting high school, and so that ?experience has been happening in parallel with this case.?

?For Kris and I, the focus of our lives has always has been and continues to be our family,? said Stier. ?And that will continue to be the driving focus of our lives and it's really what helps us be inspired by the case ? is that we want other families to have the greatest potential for success.?

When the couples first joined the legal fight, the objective was to repeal Prop. 8, and lower courts sided with them. The latest court, the Ninth Circuit Court of Appeals, said that since same-sex marriage was allowed in California for a few months in 2008 before the vote, it could not be taken away.

The Supreme Court justices could agree with that lower court decision ? in a move that would limit their ruling to couples in California ? or they could side with the backers of Prop. 8. Efforts to reach the backers, ProtectMarriage.com, for comment on Thursday were not immediately successful.

The court also could broaden out their ruling to recognize same-sex marriage in all states, as the couples' attorneys have argued, saying that the more than 30 statewide bans on gays and lesbians getting married violate the U.S. Constitution. Nine state, plus the District of Columbia, allow same-sex marriage.

?If we've learned anything through this journey, it's that when the minority rights are being oppressed by a majority the court is supposed to step in, and some times it's not always popular for them to do so,? Zarillo said. ?We would expect the court to step in and right these wrongs."

As their legal battle seemingly winds down, Stier said the couples know that the journey they embarked upon is not their's alone but will affect many others, noting she felt they ? and thousands more couples ? were ?on the cusp? of being able to finally legally wed.
?
?We are ... struck by the importance not only of being married but of a shift happening in the country that will affect generations to come,? she said. ?When we imagine the day, we're standing somewhere and taking our vows and deciding to be married, we will not only be committing to each other but will be overwhelmed, I'm sure, by the power of this decision, not only for ourselves but for the whole country.?

Meanwhile, the opposition is gearing up for the fight ? and is expecting a win. As Brian Brown, President of the National Organization for Marriage said in a statement:

"We, too, are looking forward to the court hearing. It represents the opportunity to right the wrong that was imposed by federal judges in stripping over 7 million California voters of their right to define marriage as the union of one man and one woman, the same definition that has guided civilization for thousands of years. We are confident of our position."

Related:

GOP sea change on gay rights?
Clint Eastwood to Supreme Court: Drop California's ban on same-sex marriage
US asks Supreme Court to strike down law denying benefits to same-sex couples

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Source: http://feeds.nbcnews.com/c/35002/f/653381/s/29d959f6/l/0Lusnews0Bnbcnews0N0C0Inews0C20A130C0A30C210C1740A50A460Ecouples0Eleading0Eprop0E80Efight0Ewe0Eare0Every0Eexcited0Eto0Ehave0Ethe0Eend0Ein0Esight0Dlite/story01.htm

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Friday, March 22, 2013

Pocket Spotlight Turns Your Smartphone Into a Tiny Photography Studio

Your smartphone's LED flash is better than nothing if you find yourself needing to take a photo in the dark. But the results are usually harsh and uneven. So if you find yourself in need of better lowlight shots but refuse to buy a real camera, the Pocket Spotlight is a reasonable compromise. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/mixZZlouHq8/pocket-spotlight-turns-your-smartphone-into-a-tiny-photography-studio

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A Nine-Year-Old Girl Got a New Ancient Flying Reptile Species Named After Her Because She Discovered It

When Daisy Morris was four years old, she found fossilized bones of a previously undiscovered species of the flying reptile beast pterosaur. Now, at nine years young, scientists have decided to name the reptile, which lived during the same time period as dinosaurs, after Daisy. It's called Vectidraco daisymorrisae. How cute. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/vP3PlS0tCe0/a-nine+year+old-girl-got-a-new-ancient-flying-reptile-species-named-after-her-because-she-discovered-it

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Spatial memory: Mapping blank spots in the cheeseboard maze

Mar. 21, 2013 ? IST Austria Professor Jozsef Csicsvari together with collaborators has succeeded in uncovering processes in which the formation of spatial memory is manifested in a map representation.

During learning, novel information is transformed into memory through the processing and encoding of information in neural circuits. In a recent publication in Neuron, IST Austria Professor Jozsef Csicsvari, together with his collaborator David Dupret at the University of Oxford, and Joseph O'Neill, postdoc in Csicsvari's group, uncovered a novel role for inhibitory interneurons in the rat hippocampus during the formation of spatial memory.

During spatial learning, space is represented in the hippocampus through plastic changes in the connections between neurons. Jozsef Csicsvari and his collaborators investigate spatial learning in rats using the cheeseboard maze apparatus. This apparatus contains many holes, some of which are selected to hide food in order to test spatial memory. During learning trials, animals learn where the rewards are located, and after a period sleep, the researchers test whether the animal can recall these reward locations. In previous work, they and others have shown that memory of space is encoded in the hippocampus through changes in the firing of excitatory pyramidal cells, the so-called "place cells."

A place cell fires when the animal arrives at a particular location. Normally, place cells always fire at the same place in an environment; however, during spatial learning the place of their firing can change to encode where the reward is found, forming memory maps.

In their new publication, the researchers investigated the timescale of map formation, showing that during spatial learning, pyramidal neuron maps representing previous and new reward locations "flicker," with both firing patterns occurring. At first, old maps and new maps fluctuate, as the animal is unsure whether the location change is transient or long-lasting. At a later stage, the new map and so the relevant new information dominates.

The scientists also investigated the contribution of inhibitory interneuron circuits to learning. They show that these interneurons, which are extensively interconnected with pyramidal cells, change their firing rates during map formation and flickering: some interneurons fire more often when the new pyramidal map fires, while others fire less often with the new map. These changes in interneuron firing were only observed during learning, not during sleep or recall. The scientists also show that the changes in firing rate are due to map-specific changes in the connections between pyramidal cells and interneurons. When a pyramidal cell is part of a new map, the strengthening of a connection with an interneuron causes an increase in the firing of this interneuron. Conversely, when a pyramidal cell is not part of a new map, the weakening of the connection with the interneuron causes a decrease in interneuron firing rate. Both, the increase and the decrease in firing rate can be beneficial for learning, allowing the regulation of plasticity between pyramidal cells and controlling the timing in their firing.

The new research therefore shows that not only excitatory neurons modify their behaviour and exhibit plastic connection changes during learning, but also the inhibitory interneuron circuits. The researchers suggest that inhibitory interneurons could be involved in map selection -- helping one map dominate and take over during learning, so that the relevant information is encoded.

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The above story is reprinted from materials provided by Institute of Science and Technology Austria.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David Dupret, Joseph O?Neill, Jozsef Csicsvari. Dynamic Reconfiguration of Hippocampal Interneuron Circuits during Spatial Learning. Neuron, 2013; DOI: 10.1016/j.neuron.2013.01.033

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/5uyDGO3mco8/130322104258.htm

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Thursday, March 21, 2013

Springhill Group: Age Healthy - DESIGN 21: Social Design Network

What you put into your body together with the right combination of diet and mental, physical, social and spiritual fitness plays a critical role in determining whether a persons ages in a healthy way.

The irony, those foods which may not be so appealing to the eyes and taste buds quite often offer the greatest health benefits. Fish, nuts, richly colored fruits and vegetables, legumes, yogurt, whole grains and plenty of water make up a great combination for the ultimate Anti-Aging Diet. You can eat your way to a healthy living.

The body?s ability to absorb nutrients weakens as the body ages. Because of this, it is significant to know the variety of sources of age-fighting foods in one?s chase to find their own personal fountain of youth. Richly colored fruits and vegetables are great antioxidants that offer vitamins A, C and E. Antioxidants help to combat free radicals that can damage cells and cause disease and deterioration.

Bioflavonoid, a more specific antioxidant found in the pigment of richly colored fruits and vegetables. Bioflavonoid alone are said to lead to better eyesight, improved cardiovascular health, increased capillary strength, improved structure of connective tissues and appearance of skin, and a stronger immune system.

To prevent heart disease high cholesterol, high blood pressure, diabetes, arthritis, osteoporosis and much more eat fish, eggs and some oils each offer omega 3 and 6 fatty acids.

A well-balanced, anti-aging diet should have phytosterols to maintain lower cholesterol levels, probiotics for digestive health, as well as calcium and iron for bone and blood health, respectively.

Always keep moving, this Is one of the greatest secret of ant-aging and whether you exercise at home, at a gym, in a class, or by yourself, the benefits are sure to be in favor of you. Remain consistent but it is also recommended that you consult your physician before beginning any exercise program.

Mental, social and spiritual fitness also promote healthy aging. Latest studies show that mental perception in aging is not necessarily, nor solely affected by the normal aging process, this is according to National Institute on Aging. In actual fact, to a greater extent of research demonstrates that depression plays a larger, critical role in whether the aging mind is unfavorably affected or deprived of its youth and memory function. New activities, hobbies, and exercise are wonderful anti-depressants. According to Healthy Aging Website list several ways to boost mental, social and spiritual wellness:

? Take a class, play games, be with people ? Pick up the phone now and call someone, just to "chat" ? Volunteer your time. Get involved with a cause you believe in or in something that interests you ? Seek out variety and challenge in your daily life ? Give of Yourself. Be generous with the most important thing you own -- your time. Volunteer: how about the Peace Corps, a local nursing home, or teach a youngster to swim. Seek Inspiration/Keep the Faith. Belief in a higher power is of paramount importance according to the contest entrants.

Source: http://www.design21sdn.com/share/22766

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